The gut ecosystem is generally known as gut flora and formally known as gut microbiome, gut microbes or gut microbiota. The ecosystem consists of microorganisms that live in our gut and generate essential regulatory molecules and chemical signals that are not produced from our own cells. Extensive research in the last 20 years has led to the discovery that 100 trillion bacteria live inside our digestive system, mostly in the lumen of the large intestine (formally known as the colon).

Among those trillions of gut bacteria in the ecosystem, there are about 1,000 different species, represented by roughly 5,000 distinct bacterial strains. Every person has a unique gut ecosystem, but there are certain combinations and collections of bacteria that are found in all healthy individuals.

Research into this ecosystem is currently a frontier science in order to ultimately improve and restore human health. In addition to providing energy sources to the colonic cells, most of the discovered molecules and signals regulate host’s pivotal physiology such as immune homeostasis, metabolic health and mental health by crossing over the gut barrier and traveling along the circulating blood system to reach targeted organs, tissues and cells. Due to its growing recognised pivotal importance in human health, the gut ecosystem is considered a critical ‘endocrine organ’ amongst scientists and endocrinologists.

Unfortunately, the ecosystem’s healthy state is dependent on a complex combination of factors: the availability of dietary elements to feed them and promote their growth, in addition to their dynamics and diversity.

Scientists discovered that chronic illnesses and health problems are attributable either wholly or partially to issues with diets, and by far represent the most serious threat to public health. Poor lifestyle is always associated with the deficiency of certain dietary elements, resulting in a stressed ecosystem producing abnormal molecule and chemical signal profiles. For example, metabolic syndrome and type 2 diabetes (T2D) are lifestyle diseases related to poor lifestyle habits and have abnormal gut flora due to the deficiency of critical dietary intake. Clinical doctors routinely provide dietary guidelines to help T2D patients manage their diseases, such as suggesting increased consumption of cereals, fruits and vegetables. Nevertheless, “changing an old, bad lifestyle can be terribly difficult” concluded the British Economical and Social Research Council a few years ago. Diabetes contributed to about 3.4 million global deaths in 2024 (1 in every 9 seconds) according to International Diabetes Federation.

Convincing scientific and clinical evidence fortunately indicates that increasing Probiomin intake reduces the risk of type 2 diabetes, overweight/obesity and cardiovascular diseases.

At NatureDrug Pty Ltd, we formulate and manufacture in collaboration with Australian TGA-licensed pharmaceutic manufacturer products, for example, tablet manufacturing  (see Figures 1), tablet packaging (see Figures 2 and 3) and packaging liquid products (see Figure 4). These products are safe, easy to consume and importantly, help to restore a healthy gut ecosystem and your system health including metabolic health.

Specifically, our products help restore good gut flora for gut and brain health and local and systemic immune health, are absorbed into blood circulation for targeted organ functional treatment, delay stomach emptying, enhance feeling of satiety and/or improve insulin secretion (See Figure 5).